The tempered glass side panel has four thumbscrews on its four corners which can be easily removed to access the spacious interior. At the bottom of the case is a non-removable power supply shroud which also hides the two 3.5-inch drive bays accessible at the other side of the chassis. There are no rubber grommets on the cable routing holes but the case offers plenty of that.
There is room for an interior slim 360mm radiator to be mounted on the front end of the chassis given the cutout allocated for it. However, it needs to be the very first component to be installed inside the chassis. Once the motherboard is installed, fitting the 360mm radiator upfront might be difficult or even impossible.
At the other side of the Refract S1 is where you can access the drive bays for 3.5-inch drives and the hidden 2.5-inch drive mounts along with the power supply. There are plenty of cable management options wherein you can use a cable tie to tie down cables. 2.5-inch and 3.5-inch drives have a very simple mechanism, simply place the drive and fasten them with a screw.